A phytochemical study of the hexane, ethyl acetate and methanolic extracts of chia (Salvia hispanica L.) seeds was conducted. The antioxidant capacity was determined on the methanolic extracts obtained from seeds and from the aerial part of the chia plant. The effect of chia seeds aqueous extract on the weight gain of Wistar rats was also analyzed. The methanolic extract of the aerial part of the plant showed 268 fold more total flavonoids (268 ± 6 mEQ) compared to the chia seeds extract (1 ± 0.2 mEQ). However, the antioxidant capacity of the methanolic extract of the aerial part of the plant was low (2.0 ± 0.1 TEAC) compared to those reported for other plant extracts. Also, no toxicity was observed in A. salina larvae for all the analyzed extracts. On the other hand, there were no significant differences (p>0.05) of weight between rats that consumed the aqueous extract of chia seeds and the control group that consumed water. There were also no changes in the consumption of food and liquids indicating that chia seeds aqueous extract did not produce the satiety effect that has been attributed to the seeds in other studies.